*Click test name for more information including; Specimen Requirements, Storage and Transport, Specimen Rejection Criteria, Turn around Time and CPT codes.

Test Name Methodology Test Description Specimen Requirements Storage and Transport Specimen Rejection Criteria Turn Around Time (TAT) CPT Codes*
Constitutional Cytogenetics Cytogenetics

Standard chromosome analysis performed on cultured fetal or placental cells.

•Fresh/Unfixed Tissue – Products of Conception (POC): Dissected chorionic villi or known fetal tissue(s) are preferred, but uterine contents or tissue of mixed fetal/maternal origin is acceptable and will be processed. Please include villi if sending tissue from a fetal demise. Place tissue in RPMI, note type(s) of tissue on test requisition. ◦POC cytogenetics only: At least 50-100 mg villi or 1-1.5 cm3 fetal tissue(s). ◦POC cytogenetics with reflex to NeoARRAY™ SNP/Cytogenetic Profile: Same. At least 50-100 mg villi or 1-1.5 cm3 fetal tissue(s).

Refrigerate specimen. Do not freeze. Use cold pack for transport, make sure cold pack is not in direct contact with specimen.

Click here to reference the specimen rejection criteria.

POC cyto w/o array: 7-21 days, POC cyto w/array : 21-35 days

88233, 88262, 88291

Cancer Cytogenetics Cytogenetics

A wide variety of abnormalities can be identified, providing both diagnostic and prognostic information. Acute leukemias, lymphomas and chronic myeloid and lymphoid disorders are examined cytogenetically in order to establish the exact nature of the acquired genetic change. Rearrangements, also known as translocations, inversions, and deletions, can usually be detected under a light microscope. In most leukemias and lymphomas, changes in chromosome number (ploidy) or chromosome structure (rearrangements) are often observed. 

"•BM Aspirate: 1-3 mL sodium heparin tube. •Peripheral Blood: 2-4 mL sodium heparin tube.
•Fresh/Unfixed Tissue - Lymph Node/Tissue Biopsy: One thin cross-section of fresh node or one representative section of solid tumor with minimum 0.5 cm3 tissue. Collect under sterile conditions as if for microbiologic culture. Place tissue in RPMI, note type(s) of tissue on test requisition.
"

Refrigerate specimen. Do not freeze. Use cold pack for transport, make sure cold pack is not in direct contact with specimen.

Click here to reference the specimen rejection criteria.

BM aspirate/blood cyto: 3-5 days, Lymph node/biopsy cyto: 3-21 days

88237, 88239, 88264, 88291

Methodology Test Name Test Description Specimen Requirements Storage and Transport Specimen Rejection Criteria Turn Around Time (TAT) CPT Codes*

*The CPT codes provided with our Test Descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.