Test Name: ABL1 Kinase Domain Mutation Analysis
Methodology: Molecular Genetics
RT-PCR and sequencing of the BCR-ABL 1 fusion transcript for qualitative detection of mutations associated with resistance to imatinib and other tyrosine kinase inhibitors. Analysis includes detection of the common T315I mutation.
• Peripheral blood: 4 mL in EDTA tube.
• Bone marrow: 2 mL in EDTA tube.
Storage and Transport
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. Ship same day as drawn whenever possible; specimens <72 hours old preferred.
Specimen Rejection Criteria
Turn Around Time (TAT): 10 Days
CPT Codes*: 81401
*The CPT codes provided with our Test Descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.