Test Name: BerEp4
Epithelial antigen is a transmembrane glycoprotein functioning as a cellular adhesion molecule. This epithelium-specific antigen is broadly distributed in epithelial cells, and displays a highly conserved expression in carcinomas. The antibody is useful in the differential diagnosis of adenocarcinoma versus malignant mesothelioma. Anti-Epithelial Antigen may also aid in detection of micrometastases in lymph nodes of patients with esophageal carcinoma as well as in differentiation between basal and squamous cell carcinomas of the skin.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type or one (1) unbaked, unstained slide cut at 4-5 microns for H&E staining (required) and two to three (2-3) positively charged unstained slides cut at 3-4 microns for each test/antibody ordered.
Storage and Transport
Use cold pack during transport of paraffin blocks and unstained slides. Cold pack should not be placed in direct contact with the specimen during shipping
Specimen Rejection Criteria
Turn Around Time (TAT): 2-3 Days
CPT Codes*: 88341, 88342, 88360
*The CPT codes provided with our Test Descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.