Test Name: Cancer Cytogenetics
A wide variety of abnormalities can be identified, providing both diagnostic and prognostic information. Acute leukemias, lymphomas and chronic myeloid and lymphoid disorders are examined cytogenetically in order to establish the exact nature of the acquired genetic change. Rearrangements, also known as translocations, inversions, and deletions, can usually be detected under a light microscope. In most leukemias and lymphomas, changes in chromosome number (ploidy) or chromosome structure (rearrangements) are often observed.
"•BM Aspirate: 1-3 mL sodium heparin tube. •Peripheral Blood: 2-4 mL sodium heparin tube.
•Fresh/Unfixed Tissue - Lymph Node/Tissue Biopsy: One thin cross-section of fresh node or one representative section of solid tumor with minimum 0.5 cm3 tissue. Collect under sterile conditions as if for microbiologic culture. Place tissue in RPMI, note type(s) of tissue on test requisition.
Storage and Transport
Refrigerate specimen. Do not freeze. Use cold pack for transport, make sure cold pack is not in direct contact with specimen.
Specimen Rejection Criteria
Turn Around Time (TAT): BM aspirate/blood cyto: 3-5 days, Lymph node/biopsy cyto: 3-21 days
CPT Codes*: 88237, 88239, 88264, 88291
*The CPT codes provided with our Test Descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.