Test Name: CD117


Methodology: IHC


Test Description

CD117/c-kit is expressed on the membrane of hematopoietic stem cells, melanocytes, mast cells, Cajal cells, germ cells, basal cells of skin, and mammary ductal epithelia. CD117 is also expressed by abnormal mast cells in mastocytoses, blasts of acute myeloid leukemias, gastrointestinal stromal tumors (GISTs).


Specimen Requirements

A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type or one (1) unbaked, unstained slide cut at 4-5 microns for H&E staining (required) and two to three (2-3) positively charged unstained slides cut at 3-4 microns for each test/antibody ordered.


Storage and Transport

Use cold pack during transport of paraffin blocks and unstained slides. Cold pack should not be placed in direct contact with the specimen during shipping


Specimen Rejection Criteria

Click here to reference the specimen rejection criteria.


Turn Around Time (TAT): 2-3 Days


CPT Codes*: 88341, 88342, 88360


*The CPT codes provided with our Test Descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.