Test Name: CD15

Methodology: IHC

Test Description

CD15 (LeuM1) is expressed on the membrane of normal myeloid cells (but not CD34+ blasts), monocytic and dendritic cells and of some epithelial cells (e.g. bronchial cells). It is also expressed by the neoplastic cells in acute myeloid leukemia and other myeloid neoplasms, Hodgkin and Reed-Sternberg cells in classical Hodgkin lymphoma and some adenocarcinomas (where it is useful in the differential diagnosis with mesothelioma, which is typically negative for this antigen).

Specimen Requirements

A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type or one (1) unbaked, unstained slide cut at 4-5 microns for H&E staining (required) and two to three (2-3) positively charged unstained slides cut at 3-4 microns for each test/antibody ordered.

Storage and Transport

Use cold pack during transport of paraffin blocks and unstained slides. Cold pack should not be placed in direct contact with the specimen during shipping

Specimen Rejection Criteria

Click here to reference the specimen rejection criteria.

Turn Around Time (TAT): 2-3 Days

CPT Codes*: 88341, 88342, 88360

*The CPT codes provided with our Test Descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.