Test Name: CD45
CD45 is expressed on the membrane of most normal and neoplastic cells of hematopoietic origin at all stages of maturation. CD45 expression is regarded as a highly useful marker of hematopoietic lineage in staining panels for poorly differentiated neoplasms. However, some hematopoietic neoplasms may be negative for CD45. These include myelomas, some plasmablastic lymphomas, some acute myeloid and lymphoblastic leukemia cases, and some cases of T-anaplastic large cell lymphoma.
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type or one (1) unbaked, unstained slide cut at 4-5 microns for H&E staining (required) and two to three (2-3) positively charged unstained slides cut at 3-4 microns for each test/antibody ordered.
Storage and Transport
Use cold pack during transport of paraffin blocks and unstained slides. Cold pack should not be placed in direct contact with the specimen during shipping
Specimen Rejection Criteria
Turn Around Time (TAT): 2-3 Days
CPT Codes*: 88341, 88342, 88360
*The CPT codes provided with our Test Descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.