Test Name: CD56
Methodology: Flow Cytometry
Staining for CD56 detects normal NK cells and subsets of CD8+ cytotoxic T-cells. Partial, weak CD56 expression may also be detected in subsets of normal plasma cells and on immature myeloid and monocytic cells in regenerative (reactive) processes. CD56 expression is present on a large variety of hematopoietic neoplasms, including T-cell lymphomas, B- and T-lymphoblastic leukemia/lymphoma, NK and T-large granular lymphocyte proliferations, acute myeloid leukemias and plasma cell neoplasms (MGUS, myeloma).
Testing for this antigen is typically performed as a part of the leukemia/lymphoma screening panel. For customized testing panels including this antigen, please contact the Medical Director of the Flow Cytometry laboratory.
Storage and Transport
Maintain specimen at room temperature. Do not refrigerate or freeze. Use cold pack for transport, making sure cold pack is not in direct contact with specimen.
Specimen Rejection Criteria
Turn Around Time (TAT): 24 hours
CPT Codes*: 88184, 88185, 88187, 88188, 88189
*The CPT codes provided with our Test Descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.