Test Name: CD59

Methodology: Flow Cytometry

Test Description

Staining for CD59 detects hematopoietic cells of all lineages. CD59 is a GPI anchor-linked protein, and it is most often used in the diagnostic work up for paroxysmal nocturnal hemoglobinuria (PNH), where loss of this CD59 expression is used to identify abnormal PNH clones in erythrocyte, monocyte and granulocyte populations.

Specimen Requirements

Testing for this antigen is typically performed as a part of the PNH analysis. For customized testing panels including this antigen, please contact the Medical Director of the Flow Cytometry laboratory.

Storage and Transport

Maintain specimen at room temperature. Do not refrigerate or freeze. Use cold pack for transport, making sure cold pack is not in direct contact with specimen.

Specimen Rejection Criteria

Click here to reference the specimen rejection criteria.

Turn Around Time (TAT): 24 hours

CPT Codes*: 88184, 88185, 88187, 88188, 88189

*The CPT codes provided with our Test Descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.