Test Name: Constitutional Cytogenetics

Methodology: Cytogenetics

Test Description

Standard chromosome analysis performed on cultured fetal or placental cells.

Specimen Requirements

•Fresh/Unfixed Tissue – Products of Conception (POC): Dissected chorionic villi or known fetal tissue(s) are preferred, but uterine contents or tissue of mixed fetal/maternal origin is acceptable and will be processed. Please include villi if sending tissue from a fetal demise. Place tissue in RPMI, note type(s) of tissue on test requisition. ◦POC cytogenetics only: At least 50-100 mg villi or 1-1.5 cm3 fetal tissue(s). ◦POC cytogenetics with reflex to NeoARRAY™ SNP/Cytogenetic Profile: Same. At least 50-100 mg villi or 1-1.5 cm3 fetal tissue(s).

Storage and Transport

Refrigerate specimen. Do not freeze. Use cold pack for transport, make sure cold pack is not in direct contact with specimen.

Specimen Rejection Criteria

Click here to reference the specimen rejection criteria.

Turn Around Time (TAT): POC cyto w/o array: 7-21 days, POC cyto w/array : 21-35 days

CPT Codes*: 88233, 88262, 88291

*The CPT codes provided with our Test Descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.