Test Name: FLAER

Methodology: Flow Cytometry

Test Description

FLAER (fluorescein-labeled proaerolysin) is a bacteria-derived prototoxin which binds directly to the glycophosphatidylinositol (GPI) anchor in the membrane of leukocytes. It is used in the flow cytometric assessment for paroxysmal nocturnal hemoglobinuria (PNH), as a direct measurement of GPI expression on granulocytes and monocytes.

Specimen Requirements

Testing for this antigen is typically performed as a part of the PNH analysis. For customized testing panels including this antigen, please contact the Medical Director of the Flow Cytometry laboratory.

Storage and Transport

Maintain specimen at room temperature. Do not refrigerate or freeze. Use cold pack for transport, making sure cold pack is not in direct contact with specimen.

Specimen Rejection Criteria

Click here to reference the specimen rejection criteria.

Turn Around Time (TAT): 24 hours

CPT Codes*: 88184, 88185, 88187, 88188, 88189

*The CPT codes provided with our Test Descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.