Test Name: HPV Genotyping 16, 18/45

Methodology: RNA - Hologic Panther

Test Description

This assay is a nucleic acid amplification test for the qualitative detection of E6/E7 viral messenger RNA (mRNA) in cervical specimens from women with HPV+ results. This test can differentiate HPV 16 from HPV 18 and/or 45, but not between HPV 18 and 45. Studies show that targeting E6/E7 mRNA identifies the presence and activity of a high-risk HPV infection.

Specimen Requirements

Cervical Specimens. Acceptable specimen collection/transport containers are:
•ThinPrep® Pap Vial
•APTIMA® Specimen Transfer Tube containing 1 ml of ThinPrep® or SurePath™ Pap Vial contents (vortex vial before transfer)

Storage and Transport

Specimens can be shipped and stored at 2 - 30°C. If shipping temperatures exceeding 30°C are anticipated, use cool plack. Viability after transfer to collection/transport tube is:
•ThinPrep® Pap Vial: 30 days
•APTIMA® Specimen Transfer Tube: 30 days containing ThinPrep® aliquot

Specimen Rejection Criteria

Click here to reference the specimen rejection criteria.

Turn Around Time (TAT): 2 - 4 Days

CPT Codes*: 87625 (add 87624 when reflexed from HPV High Risk)

*The CPT codes provided with our Test Descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.