Test Name: IgM

Methodology: IHC

Test Description

IgM is normally expressed on membranes of B-cells in the germinal center and mantle zones of reactive follicles, as well as in subsets of polyclonal plasma cells. It is also expressed in the plasma cells associated with some B-lymphoid neoplasms (lymphoplasmacytic lymphoma, CLL/SLL, marginal zone lymphoma) and in very rare cases of plasma cell myeloma.

Specimen Requirements

A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type or one (1) unbaked, unstained slide cut at 4-5 microns for H&E staining (required) and two to three (2-3) positively charged unstained slides cut at 3-4 microns for each test/antibody ordered.

Storage and Transport

Use cold pack during transport of paraffin blocks and unstained slides. Cold pack should not be placed in direct contact with the specimen during shipping

Specimen Rejection Criteria

Click here to reference the specimen rejection criteria.

Turn Around Time (TAT): 2-3 Days

CPT Codes*: 88341, 88342, 88360

*The CPT codes provided with our Test Descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.