Test Name: JAK2 Exons 12 &14 Mutation Analysis

Methodology: Molecular Genetics

Test Description

The JAK2 Exon 12 & 14 Mutation Analysis assay uses next-generation sequencing (NGS) technology to provide an assessment of the JAK2 gene for the detection of mutations within select regions of exons 12 and 14 in DNA extracted from whole blood and bone marrow with known involvement in myeloproliferative neoplasms (MPN).

Specimen Requirements

•Peripheral blood: 4 mL in EDTA tube.
•Bone marrow: 2 mL in EDTA tube.

Storage and Transport

Use cold pack for transport, making sure cold pack is not in direct contact with specimen. Ship same day as drawn whenever possible; specimens <72 hours old preferred.

Specimen Rejection Criteria

Click here to reference the specimen rejection criteria.

Turn Around Time (TAT): 7-10 Days

CPT Codes*: 81270, 81403

*The CPT codes provided with our Test Descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.