Test Name: KRAS & BRAF Mutation Analysis 


Methodology: Molecular Genetics


Test Description

Concurrent analysis of KRAS and BRAF gene regions including KRAS exons 2 and 3 (with mutation detection in codons 12, 13, 59, and 61) and BRAF exon 15 to detect V600 mutations and more. Tumor enrichment is performed before extraction.


Specimen Requirements

FFPE solid tumor tissue: Paraffin block is preferred. Alternatively, send 1 H&E slide plus 5-10 unstained slides cut at 5 or more microns. Please use positively-charged slides and 10% NBF fixative. Do not use zinc fixatives.


Storage and Transport

Use cold pack for transporting block during summer to prevent block from melting. Slides can be packed at room temperature.


Specimen Rejection Criteria

Click here to reference the specimen rejection criteria.


Turn Around Time (TAT): 7 Days


CPT Codes*: 81210, 81275


*The CPT codes provided with our Test Descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.