Test Name: LAMBDA

Methodology: Flow Cytometry

Test Description

Staining for immunoglobulin lambda light chain highlights subsets of mature B-cells (by surface staining) and plasma cells (by intracytoplasmic staining), as well as the neoplastic cells in mature B-cell lymphomas and plasma cell neoplasms. The kappa:lambda ratio is used to assess these neoplasms for clonality.

Specimen Requirements

Testing for this surface antigen is typically performed as a part of the leukemia/lymphoma screening panel, while testing for cytoplasmic lambda is part of the plasma cell neoplasm add-on panel. For customized testing panels including this antigen, please contact the Medical Director of the Flow Cytometry laboratory.

Storage and Transport

Maintain specimen at room temperature. Do not refrigerate or freeze. Use cold pack for transport, making sure cold pack is not in direct contact with specimen.

Specimen Rejection Criteria

Click here to reference the specimen rejection criteria.

Turn Around Time (TAT): 24 hours

CPT Codes*: 88184, 88185, 88187, 88188, 88189

*The CPT codes provided with our Test Descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.