Test Name: PIK3CA Mutation Analysis
Methodology: Molecular Genetics
The PIK3CA Mutation Analysis assay uses next-generation sequencing (NGS) technology to provide an assessment of the PIK3CA gene in select regions of exons 10 and 21 in human genomic DNA isolated from formalin-fixed paraffin-embedded (FFPE) tissue.
•FFPE tissue: Paraffin block is preferred. Alternatively, send 1 H&E slide plus 5-10 unstained slides cut at 5 or more microns. Please use positively-charged slides and 10% NBF fixative. Do not use zinc fixatives.
Storage and Transport
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. Slides can be packed at room temperature.
Specimen Rejection Criteria
Turn Around Time (TAT): 7-10 Days
CPT Codes*: 81404
*The CPT codes provided with our Test Descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.