Test Name: TREPONEMA PALLIDUM
Spirochete (Treponema pallidum) is the causative agent of syphilis. In the past, localization of the spirochete agent was achieved with silver stains such as Steiner’s and/or Warthin-Starry. Treponema pallidum can now be successfully localized with immunohistochemical techniques in formalin-fixed paraffinembedded tissue. Studies have shown this offers a substantial advantage over silver-techniques in both sensitivity and specificity. The antibody consists of a rabbit purified IgG fraction and is highly specific for spirochete (1).
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type or one (1) unbaked, unstained slide cut at 4-5 microns for H&E staining (required) and two to three (2-3) positively charged unstained slides cut at 3-4 microns for each test/antibody ordered.
Storage and Transport
Use cold pack during transport of paraffin blocks and unstained slides. Cold pack should not be placed in direct contact with the specimen during shipping
Specimen Rejection Criteria
Turn Around Time (TAT): 2-3 Days
CPT Codes*: 88341, 88342, 88360
*The CPT codes provided with our Test Descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed.